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1076225-26-7

1076225-26-7 structure
1076225-26-7 structure
  • Name: (rac)-PF-998425
  • Chemical Name: (rac)-PF-998425
  • CAS Number: 1076225-26-7
  • Molecular Formula: C14H14F3NO
  • Molecular Weight: 269.26
  • Catalog: Research Areas Endocrinology
  • Create Date: 2022-02-20 15:42:25
  • Modify Date: 2024-01-19 21:10:43
  • (rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays, respectively. (rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].

Name (rac)-PF-998425
Description (rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays, respectively. (rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].
Related Catalog
References

[1]. Li JJ, et al. Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J Med Chem. 2008;51(21):7010-7014.

Molecular Formula C14H14F3NO
Molecular Weight 269.26