(S)-Propafenone

Modify Date: 2024-01-13 18:45:01

(S)-Propafenone Structure
(S)-Propafenone structure
Common Name (S)-Propafenone
CAS Number 107381-32-8 Molecular Weight 341.44400
Density 1.096g/cm3 Boiling Point 519.6ºC at 760mmHg
Molecular Formula C21H27NO3 Melting Point N/A
MSDS N/A Flash Point 268ºC

 Use of (S)-Propafenone


(S)-Propafenone ((S)-SA-79) is the S-enantiomer of Propafenone. (S)-Propafenone ((S)-SA-79) exerts beta-blocking action and the sodium channel-dependent antiarrhythmic class 1 activity[1].

 Names

Name (S)-Propafenone

 (S)-Propafenone Biological Activity

Description (S)-Propafenone ((S)-SA-79) is the S-enantiomer of Propafenone. (S)-Propafenone ((S)-SA-79) exerts beta-blocking action and the sodium channel-dependent antiarrhythmic class 1 activity[1].
Related Catalog
References

[1]. Stoschitzky K, et al. Different stereoselective effects of (R)- and (S)-propafenone: clinical pharmacologic, electrophysiologic, and radioligand binding studies. Clin Pharmacol Ther. 1990 Jun;47(6):740-6.

 Chemical & Physical Properties

Density 1.096g/cm3
Boiling Point 519.6ºC at 760mmHg
Molecular Formula C21H27NO3
Molecular Weight 341.44400
Flash Point 268ºC
Exact Mass 341.19900
PSA 58.56000
LogP 3.63230
Vapour Pressure 1.27E-11mmHg at 25°C
Index of Refraction 1.557

 Safety Information

HS Code 2922509090

 Synthetic Route

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(S)-Propafenone Structure

(S)-Propafenone

CAS#:107381-32-8

Literature: US4945114 A1, ;

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(S)-Propafenone Structure

(S)-Propafenone

CAS#:107381-32-8

Literature: Journal of Medicinal Chemistry, , vol. 54, # 21 p. 7477 - 7485

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(S)-Propafenone Structure

(S)-Propafenone

CAS#:107381-32-8

Literature: Liebigs Annalen der Chemie, , p. 561 - 564

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%