(S)-Propafenone

Names

[ Name ]:
(S)-Propafenone

Biological Activity

[Description]:

(S)-Propafenone ((S)-SA-79) is the S-enantiomer of Propafenone. (S)-Propafenone ((S)-SA-79) exerts beta-blocking action and the sodium channel-dependent antiarrhythmic class 1 activity[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Stoschitzky K, et al. Different stereoselective effects of (R)- and (S)-propafenone: clinical pharmacologic, electrophysiologic, and radioligand binding studies. Clin Pharmacol Ther. 1990 Jun;47(6):740-6.

Chemical & Physical Properties

[ Density]:
1.096g/cm3

[ Boiling Point ]:
519.6ºC at 760mmHg

[ Molecular Formula ]:
C₂₁H₂₇NO₃

[ Molecular Weight ]:
341.44400

[ Flash Point ]:
268ºC

[ Exact Mass ]:
341.19900

[ PSA ]:
58.56000

[ LogP ]:
3.63230

[ Vapour Pressure ]:
1.27E-11mmHg at 25°C

[ Index of Refraction ]:
1.557

Safety Information

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%