ML359
Modify Date: 2025-07-25 14:57:26
ML359 structure
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Common Name | ML359 | ||
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| CAS Number | 1069858-99-6 | Molecular Weight | 417.93 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H28ClNO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ML359ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM; displays >100-fold selectivity over other thiol isomerases (Erp5, Thioredoxin, Thioredoxin reductase); shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro. |
| Name | ML359 |
|---|
| Description | ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM; displays >100-fold selectivity over other thiol isomerases (Erp5, Thioredoxin, Thioredoxin reductase); shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro. |
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| References | References 1. Khodier C, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. View Related Products by Target Protein Disulfide Isomerase (PDI) |
| Molecular Formula | C23H28ClNO4 |
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| Molecular Weight | 417.93 |
| Storage condition | 2-8°C |