ML359

Names

[ Name ]:
ML359

Biological Activity

[Description]:

ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM; displays >100-fold selectivity over other thiol isomerases (Erp5, Thioredoxin, Thioredoxin reductase); shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro.

[References]

References 1. Khodier C, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. View Related Products by Target Protein Disulfide Isomerase (PDI)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₈ClNO₄

[ Molecular Weight ]:
417.93

[ Storage condition ]:
2-8°C

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.