CBP/p300-IN-21

Modify Date: 2025-08-21 13:55:22

CBP/p300-IN-21 structure	Common Name	CBP/p300-IN-21
	CAS Number	1065581-69-2	Molecular Weight	357.79
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₆ClNO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CBP/p300-IN-21

CBP/p300-IN-21 (Compound 5d) is a selective CBP/p300 inhibitor (IC50: 0.07 and 1.755 μM for p300 and CBP). CBP/p300-IN-21 decreases H3K18Ac level. CBP/p300-IN-21 inhibits growth of 4T1 tumor growth in mice[1].

Name	CBP/p300-IN-21

Description	CBP/p300-IN-21 (Compound 5d) is a selective CBP/p300 inhibitor (IC50: 0.07 and 1.755 μM for p300 and CBP). CBP/p300-IN-21 decreases H3K18Ac level. CBP/p300-IN-21 inhibits growth of 4T1 tumor growth in mice[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Acetyltransferase Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	0.07 and 1.755 μM for p300 and CBP[1]
References	[1]. Zhong X, et al. Discovery of berberine analogs as potent and highly selective p300/CBP HAT inhibitors. Bioorg Chem. 2023 Sep;138:106597.

Molecular Formula	C₁₉H₁₆ClNO₄
Molecular Weight	357.79

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