2',7'-dichlorodihydrofluorescein

Modify Date: 2024-01-06 19:04:21

2',7'-dichlorodihydrofluorescein Structure
2',7'-dichlorodihydrofluorescein structure
Common Name 2',7'-dichlorodihydrofluorescein
CAS Number 106070-31-9 Molecular Weight 403.21200
Density 1.583g/cm3 Boiling Point 553.7ºC at 760mmHg
Molecular Formula C20H12Cl2O5 Melting Point N/A
MSDS N/A Flash Point 288.7ºC

 Use of 2',7'-dichlorodihydrofluorescein


2,7-Dichlorodihydrofluorescein (DCFH2) is a non-fluorescent probe. 2,7-Dichlorodihydrofluorescein yields the highly fluorescent 2′,7′-dichlorofluorescein (DCF) that can be used for reactive oxygen species measurement[1][2].

 Names

Name 2-(3,6-dichloro-2,7-dihydroxy-9H-xanthen-9-yl)benzoic acid
Synonym More Synonyms

 2',7'-dichlorodihydrofluorescein Biological Activity

Description 2,7-Dichlorodihydrofluorescein (DCFH2) is a non-fluorescent probe. 2,7-Dichlorodihydrofluorescein yields the highly fluorescent 2′,7′-dichlorofluorescein (DCF) that can be used for reactive oxygen species measurement[1][2].
Related Catalog
References

[1]. Reiniers MJ, et al. Preparation and Practical Applications of 2',7'-Dichlorodihydrofluorescein in Redox Assays. Anal Chem. 2017 Apr 4;89(7):3853-3857.  

[2]. Chen X, et al. 2',7'-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy. Free Radic Res. 2010 Jun;44(6):587-604.  

 Chemical & Physical Properties

Density 1.583g/cm3
Boiling Point 553.7ºC at 760mmHg
Molecular Formula C20H12Cl2O5
Molecular Weight 403.21200
Flash Point 288.7ºC
Exact Mass 402.00600
PSA 86.99000
LogP 5.38870
Vapour Pressure 4.26E-13mmHg at 25°C
Index of Refraction 1.717
Storage condition 2-8°C

 Safety Information

HS Code 2932999099

 Synthetic Route

~79%

2',7'-dichlorodihydrofluorescein Structure

2',7'-dichlorod...

CAS#:106070-31-9

Literature: Afri, Michal; Frimer, Aryeh A.; Cohen, Yael Chemistry and Physics of Lipids, 2004 , vol. 131, # 1 p. 123 - 133

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2',7'-dichlorodihydrofluorescein Structure

2',7'-dichlorod...

CAS#:106070-31-9

Literature: Cellamare, Barbara M.; Fini, Paola; Agostiano, Angela; Sortino, Salvatore; Cosma, Pinalysa Photochemistry and Photobiology, 2013 , vol. 89, # 2 p. 432 - 441

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2',7'-dichlorofluorescin
dichlorodihydrofluorescein
2`,7`-dichlorodihydrofluorescein
2',7'-dihydrodichlorofluorescein