Q94 hydrochloride
Modify Date: 2024-01-02 15:56:50
Q94 hydrochloride structure
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Common Name | Q94 hydrochloride | ||
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| CAS Number | 1052076-77-3 | Molecular Weight | 369.29 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H18Cl2N2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Q94 hydrochlorideQ94 hydrochloride, a selective PAR1 antagonist (IC50=916 nM), can selectively block PAR1/Gαq interaction and signalling. Q94 hydrochloride blocks PAR1-mediated increases in both CCL2 mRNA and protein levels in a dose-dependent manner. Q94 hydrochloride also completely blocks thrombin-induced ERK1/2 and MLC phosphorylation[1]. |
| Name | 2-Benzyl-1-(4-chlorobenzyl)-1H-benzimidazole hydrochloride (1:1) |
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| Synonym | More Synonyms |
| Description | Q94 hydrochloride, a selective PAR1 antagonist (IC50=916 nM), can selectively block PAR1/Gαq interaction and signalling. Q94 hydrochloride blocks PAR1-mediated increases in both CCL2 mRNA and protein levels in a dose-dependent manner. Q94 hydrochloride also completely blocks thrombin-induced ERK1/2 and MLC phosphorylation[1]. |
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| Related Catalog | |
| Target |
IC50: 916 nM (PAR1)[1]. |
| References |
| Molecular Formula | C21H18Cl2N2 |
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| Molecular Weight | 369.29 |
| Exact Mass | 368.084717 |
| 2-Benzyl-1-(4-chlorobenzyl)-1H-benzimidazole hydrochloride (1:1) |
| 1H-Benzimidazole, 1-[(4-chlorophenyl)methyl]-2-(phenylmethyl)-, hydrochloride (1:1) |