C450-0730

Modify Date: 2025-11-27 18:51:30

C450-0730 Structure
C450-0730 structure
Common Name C450-0730
CAS Number 1036730-46-7 Molecular Weight 478.004
Density N/A Boiling Point N/A
Molecular Formula C23H28ClN3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of C450-0730


C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM; competes for the AI-1 binding site of LuxN; inhibition for mutant LuxN G271D, R245L, and S184N is similar to that required to inhibit wild-type LuxN.

 Names

Name C450-0730

 C450-0730 Biological Activity

Description C450-0730 is a potent LuxN antagonist that antagonizes LuxN-AI-1 binding with IC50 of 2.7 uM; competes for the AI-1 binding site of LuxN; inhibition for mutant LuxN G271D, R245L, and S184N is similar to that required to inhibit wild-type LuxN.
References References 1. Swem LR, et al. Cell. 2008 Aug 8;134(3):461-73. View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C23H28ClN3O4S
Molecular Weight 478.004
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