Ethyl 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate

Modify Date: 2024-01-11 11:52:46

Ethyl 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate Structure
Ethyl 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate structure
Common Name Ethyl 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate
CAS Number 10350-10-4 Molecular Weight 197.188
Density 1.3±0.1 g/cm3 Boiling Point 446.0±40.0 °C at 760 mmHg
Molecular Formula C9H11NO4 Melting Point 216-222ºC
MSDS N/A Flash Point 223.6±27.3 °C

 Names

Name Ethyl 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 446.0±40.0 °C at 760 mmHg
Melting Point 216-222ºC
Molecular Formula C9H11NO4
Molecular Weight 197.188
Flash Point 223.6±27.3 °C
Exact Mass 197.068802
PSA 79.39000
LogP 0.04
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.571
Storage condition 2-8°C

 MSDS

Name: Ethyl-4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate Material Safety Data Sheet
Synonym:
CAS: 10350-10-4
Section 1 - Chemical Product MSDS Name: Ethyl-4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate Material Safety Data Sheet
Synonym:

SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
10350-10-4 Ethyl-4-hydroxy-6-methyl-2-oxo-1,2-dih 95+% unlisted
Hazard Symbols: XN
Risk Phrases: 20/21/22 36/37/38
SECTION 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Potential Health Effects The toxicological properties of this material have not been investigated. Use appropriate procedures to prevent opportunities for direct contact with the skin or eyes and to prevent inhalation.
SECTION 4 - FIRST AID MEASURES
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Wash mouth out with water. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:


SECTION 5 - FIRE FIGHTING MEASURES
General Information:
Not available.
Extinguishing Media:
Not available.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.
SECTION 7 - HANDLING and STORAGE
Handling:
Container should be opened by a technically qualified person.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances.
SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Exposure Limits CAS# 10350-10-4: Personal Protective Equipment
Eyes:
Not available.
Skin:
Not available.
Clothing:
Not available.
Respirators:
Not available.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: White
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 205 - 207 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C9H11NO4
Molecular Weight: 197.19
SECTION 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
High temperatures, incompatible materials.
Incompatibilities with Other Materials:
Strong bases, strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, carbon dioxide.
Hazardous Polymerization: Not available.
SECTION 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 10350-10-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Ethyl-4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate - Not listed by ACGIH, IARC, or NTP.
SECTION 12 - ECOLOGICAL INFORMATION
SECTION 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations.
SECTION 14 - TRANSPORT INFORMATION IATA
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing Group: III IMO
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing Group: III RID/ADR
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing group: III
SECTION 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R 36/37/38 Irritating to eyes, respiratory system and skin.
Safety Phrases:
S 22 Do not breathe dust. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 10350-10-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 10350-10-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 10350-10-4 is not listed on the TSCA inventory. It is for research and development use only.
SECTION 16 - ADDITIONAL INFORMATION
MSDS Creation Date: 10/08/2004 Revision #0 Date: Original. The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages.

SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xn
Risk Phrases 22-36/37/38
Safety Phrases 22-26-36/37/39
RIDADR NONH for all modes of transport
HS Code 2933399090

 Synthetic Route

~77%

Ethyl 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate Structure

Ethyl 4-hydroxy...

CAS#:10350-10-4

Literature: Stadlbauer, Wolfgang; Fiala, Werner; Fischer, Michaela; Hojas, Gerhard Advanced Synthesis and Catalysis, 2000 , vol. 342, # 1 p. 33 - 39

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Ethyl-4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridin-3-carboxylat
Ethyl2,4-dihydroxy-6-methyl-3-pyridinecarboxylate
Ethyl 2,4-dihydroxy-6-methylnicotinate
3-pyridinecarboxylic acid, 2,4-dihydroxy-6-methyl-, ethyl ester
2,4-Dihydroxy-6-methyl-3-pyridine carboxylic acid ethyl ester
3-Pyridinecarboxylic acid, 1,2-dihydro-4-hydroxy-6-methyl-2-oxo-, ethyl ester
ethyl 2,4-dihydroxy-6-methylpyridine-3-carboxylate
Ethyl 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate
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