A-940894

Modify Date: 2025-08-25 17:06:16

A-940894 structure	Common Name	A-940894
	CAS Number	1027330-82-0	Molecular Weight	295.38200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₂₁N₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of A-940894

A-940894 is a potent histamine H4 receptor antagonist, with Ki values of 7.6 nM (rat H4) and 71 nM (human H4). A-940894 exhibits with anti-inflammatory properties[1].

Name	4-piperazin-1-yl-6,7-dihydro-5H-benzo[1,2]cyclohepta[3,4-b]pyrimidin-2-amine
Synonym	More Synonyms

Description	A-940894 is a potent histamine H4 receptor antagonist, with Ki values of 7.6 nM (rat H4) and 71 nM (human H4). A-940894 exhibits with anti-inflammatory properties[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	Ki: 7.6 nM (rat H4), 71 nM (human H4)[1].
References	[1]. M I Strakhova, et al. In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties. Br J Pharmacol. 2009 May;157(1):44-54.

Molecular Formula	C₁₇H₂₁N₅
Molecular Weight	295.38200
Exact Mass	295.18000
PSA	67.80000
LogP	1.94800

2,4-diamino-5,6-disubstituted pyrimidine,9

UNII-8U5620H545

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A-940894

Use of A-940894

Names

A-940894 Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.