Valbenazine
Modify Date: 2025-08-25 18:50:31
Valbenazine structure
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Common Name | Valbenazine | ||
|---|---|---|---|---|
| CAS Number | 1025504-45-3 | Molecular Weight | 418.569 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 507.2±50.0 °C at 760 mmHg | |
| Molecular Formula | C24H38N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 260.6±30.1 °C | |
Use of ValbenazineValbenazine is a prodrug of the (+)-α isomer of tetrabenazine for tardive syndrome therapy, and inhibits VMAT2 function. |
| Name | [(2R,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl] (2S)-2-amino-3-methylbutanoate |
|---|---|
| Synonym | More Synonyms |
| Description | Valbenazine is a prodrug of the (+)-α isomer of tetrabenazine for tardive syndrome therapy, and inhibits VMAT2 function. |
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| Related Catalog | |
| In Vivo | Valbenazine shows a distinctive improvement in tardive dyskinesia symptoms during the successful Phase II trial[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 507.2±50.0 °C at 760 mmHg |
| Molecular Formula | C24H38N2O4 |
| Molecular Weight | 418.569 |
| Flash Point | 260.6±30.1 °C |
| Exact Mass | 418.283173 |
| PSA | 74.02000 |
| LogP | 4.31 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.548 |
| Storage condition | 2-8℃ |
| Ingrezza |
| (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl L-valinate |
| NBI-98854 |
| L-Valine, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester |
| UNII:54K37P50KH |
| (2R,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizin-2-yl L-valinate |
| Valbenazine |