KCNQ2/3 activator-1

Modify Date: 2025-08-26 01:42:43

KCNQ2/3 activator-1 Structure
KCNQ2/3 activator-1 structure
Common Name KCNQ2/3 activator-1
CAS Number 1009344-33-5 Molecular Weight 368.488
Density 1.1±0.1 g/cm3 Boiling Point 541.8±50.0 °C at 760 mmHg
Molecular Formula C23H29FN2O Melting Point N/A
MSDS N/A Flash Point 281.4±30.1 °C

 Use of KCNQ2/3 activator-1


KCNQ2/3 activator-1 is an activator of Kv7.2/Kv7.3 (KCNQ2/3) potassium channel. KCNQ2/3 activator-1 has the potential in relieving pain (the main problem from medical treatment) (extracted from patent WO2021113757A1, compound A)[1].

 Names

Name N-[4-(6-Fluoro-3,4-dihydro-2(1H)-isoquinolinyl)-2,6-dimethylphenyl]-3,3-dimethylbutanamide
Synonym More Synonyms

 KCNQ2/3 activator-1 Biological Activity

Description KCNQ2/3 activator-1 is an activator of Kv7.2/Kv7.3 (KCNQ2/3) potassium channel. KCNQ2/3 activator-1 has the potential in relieving pain (the main problem from medical treatment) (extracted from patent WO2021113757A1, compound A)[1].
Related Catalog
References

[1]. James Philip, et al. Use of a kv7 potassium channel opener for treating pain. Patent WO2021113757A1.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 541.8±50.0 °C at 760 mmHg
Molecular Formula C23H29FN2O
Molecular Weight 368.488
Flash Point 281.4±30.1 °C
Exact Mass 368.226379
LogP 5.28
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.579
Storage condition -20°C

 Synonyms

Butanamide, N-[4-(6-fluoro-3,4-dihydro-2(1H)-isoquinolinyl)-2,6-dimethylphenyl]-3,3-dimethyl-
N-[4-(6-Fluoro-3,4-dihydro-2(1H)-isoquinolinyl)-2,6-dimethylphenyl]-3,3-dimethylbutanamide
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