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Product Name: Rifamycin,3-[(1-piperazinylimino)methyl]-
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13292-45-0

13292-45-0 structure

13292-45-0 structure

Name: Rifamycin,3-[(1-piperazinylimino)methyl]-
Chemical Name: N-Demethyl Rifampin
CAS Number: 13292-45-0
Molecular Formula: C₄₂H₅₆N₄O₁₂
Molecular Weight: 808.91400
Catalog: API Antibiotics Rifamycin
Create Date: 2018-08-26 10:32:12
Modify Date: 2025-08-27 09:46:26

Name	N-Demethyl Rifampin
Synonyms	4-N-Demethylrifampicin rifaldehyde piperazin-1-ylhydrazone Rifampicin AF/AP 3-(piperazin-1-ylimino-methyl)-rifamycin N-Demethylrifampin AF/AP N-Demethylrifampicin Rifampicin AF/A 3-(piperidinyliminomethyl)rifamycin SV Demethylrifampicin

Density	1.35g/cm3
Molecular Formula	C₄₂H₅₆N₄O₁₂
Molecular Weight	808.91400
Exact Mass	808.38900
PSA	228.94000
LogP	4.39790
Index of Refraction	1.631

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KD1923000

CHEMICAL NAME :: 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl -8-(N-1-piperazinylfo rmimidoyl)-, 21- acetate

CAS REGISTRY NUMBER :: 13292-45-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C42-H56-N4-O12

MOLECULAR WEIGHT :: 809.02

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 695 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 100 mg/L

REFERENCE :: BBRCA9 Biochemical and Biophysical Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 60,96,1974

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