(-)-Cleistenolide
Modify Date: 2025-08-26 23:07:32
(-)-Cleistenolide structure
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Common Name | (-)-Cleistenolide | ||
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| CAS Number | 1003600-48-3 | Molecular Weight | 362.33 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H18O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (-)-Cleistenolide(-)-Cleistenolide is a α,β-unsaturated δ-lactone isolated from Cleistochlamys kirkii Oliver. (-)-Cleistenolide has antibacterial and antitumor activity[1]. |
| Name | (-)-Cleistenolide |
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| Description | (-)-Cleistenolide is a α,β-unsaturated δ-lactone isolated from Cleistochlamys kirkii Oliver. (-)-Cleistenolide has antibacterial and antitumor activity[1]. |
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| Related Catalog | |
| In Vitro | (-)-Cleistenolide (compound 1) exhibits potent cytotoxicity against cancer cell lines and low cytotoxicity in normal cells MRC-5[1]. Cell Cytotoxicity Assay Cell Line: K562, HL-60, Jurkat, Raji, MCF-7, MDA-MB 231, HeLa, A549 and MRC-5[1] Concentration: 0-100 μM Incubation Time: Result: Exhibited potent cytotoxicity against cancer cell lines with IC50s of 7.65 μM, 1.21 μM, 14.22 μM, 36.94 μM, 26.07 μM, 2.25 μM, 7.32 μM and 16.34 μM in K562, HL-60, Jurkat, Raji, MCF-7, MDA-MB 231, HeLa and A549, respectively; and had low cytotoxicity in normal cells MRC-5 with an IC50 over 100 μM. |
| References |
| Molecular Formula | C18H18O8 |
|---|---|
| Molecular Weight | 362.33 |
| InChIKey | LLQJCQPOMJOCDA-INMHGKMJSA-N |
| SMILES | CC(=O)OC1C=CC(=O)OC1C(COC(=O)c1ccccc1)OC(C)=O |