53734-74-0
53734-74-0 structure
- Name: neorauflavane
- Chemical Name: N-Methyl-1,3-diphenyl-2-propanamine
- CAS Number: 53734-74-0
- Molecular Formula: C21H22O5
- Molecular Weight: 354.40
- Catalog: Natural product Flavonoids
- Create Date: 2017-05-06 02:00:31
- Modify Date: 2024-01-10 16:31:04
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Neorauflavane is a potent tyrosinase inhibitor derived from Campylotropis hirtella, with an IC50 value of 30 nM for tyrosinase monophenolase activity and an IC50 value of 500 nM for diphenolase activity. Neorauflavane can effectively reduce the melanin content of B16 melanoma cells[1].
| Name | N-Methyl-1,3-diphenyl-2-propanamine |
|---|---|
| Synonyms |
4-[(7R)-5-Methoxy-2,2-dimethyl-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-7-yl]-1,3-benzenediol
1,3-Benzenediol, 4-[(7R)-7,8-dihydro-5-methoxy-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-yl]- |
| Description | Neorauflavane is a potent tyrosinase inhibitor derived from Campylotropis hirtella, with an IC50 value of 30 nM for tyrosinase monophenolase activity and an IC50 value of 500 nM for diphenolase activity. Neorauflavane can effectively reduce the melanin content of B16 melanoma cells[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 552.9±50.0 °C at 760 mmHg |
| Molecular Formula | C21H22O5 |
| Molecular Weight | 354.40 |
| Flash Point | 288.2±30.1 °C |
| Exact Mass | 354.146729 |
| PSA | 68.15000 |
| LogP | 3.96 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.609 |
| Hazard Codes | Xi |
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