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77308-57-7

77308-57-7 structure
77308-57-7 structure
  • Name: NSC-77053
  • Chemical Name: 2-(9H-fluorene-2-carbonyl)benzoic acid
  • CAS Number: 77308-57-7
  • Molecular Formula: C21H14O3
  • Molecular Weight: 314.33400
  • Catalog: Research Areas Others
  • Create Date: 2016-01-14 14:15:28
  • Modify Date: 2024-02-01 19:13:15
  • NSC-77053 is a potent BoNT/E inhibitor with an IC50 and a Ki of 2.4 μM and 1.29 μM, respectively[1].

Name 2-(9H-fluorene-2-carbonyl)benzoic acid
Description NSC-77053 is a potent BoNT/E inhibitor with an IC50 and a Ki of 2.4 μM and 1.29 μM, respectively[1].
Related Catalog
Target

IC50: 2.4 μM (BoNT/E)[1]

References

[1]. Yuchen Zhou, et al. Identification of small molecule inhibitors of botulinum neurotoxin serotype E via footprint similarity. Bioorg Med Chem. 2016 Oct 15;24(20):4875-4889.  

Density 1.315g/cm3
Boiling Point 586.6ºC at 760 mmHg
Molecular Formula C21H14O3
Molecular Weight 314.33400
Flash Point 322.6ºC
Exact Mass 314.09400
PSA 54.37000
LogP 4.18700
Index of Refraction 1.682

~79%

77308-57-7 structure

77308-57-7

Literature: Guilhemat, Robert; Pereyre, Michel; Petraud, Michel Bulletin de la Societe Chimique de France, 1980 , vol. 2, # 7-8 p. 334 - 344
Precursor  2

DownStream  2