70132-51-3
70132-51-3 structure
- Name: Pimonidazole hydrochloride
- Chemical Name: 1-(2-nitroimidazol-1-yl)-3-piperidin-1-ylpropan-2-ol,hydrochloride
- CAS Number: 70132-51-3
- Molecular Formula: C11H19ClN4O3
- Molecular Weight: 290.74700
- Catalog: Research Areas Cancer
- Create Date: 2016-02-04 09:36:06
- Modify Date: 2024-01-10 11:25:11
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Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor[1]. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia [2].
| Name | 1-(2-nitroimidazol-1-yl)-3-piperidin-1-ylpropan-2-ol,hydrochloride |
|---|---|
| Synonyms |
Ro 03-8799
Pimonidazole hydrochloride 1-(2-nitro-1h-imidazol-1-yl)-3-(piperidin-1-yl)propan-2-ol hydrochloride(1:1) Pimonidazole HCl |
| Description | Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor[1]. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia [2]. |
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| Related Catalog | |
| References |
| Boiling Point | 490.5ºC at 760 mmHg |
|---|---|
| Molecular Formula | C11H19ClN4O3 |
| Molecular Weight | 290.74700 |
| Flash Point | 250.5ºC |
| Exact Mass | 290.11500 |
| PSA | 87.11000 |
| LogP | 1.90120 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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