| Name | 4-(Trifluoromethyl)biphenyl-2-carboxylic acid |
|---|---|
| Synonyms |
XENALIPIN
4'-(Trifluoromethyl)-2-biphenylcarboxylic acid 4'-(trifluoromethyl)biphenyl-2-carboxylic acid 2-[4-(trifluoromethyl)phenyl]benzoic acid MFCD00075353 [1,1'-Biphenyl]-2-carboxylic acid, 4'-(trifluoromethyl)- 4'-(Trifluoromethyl)-1,1'-biphenyl-2-carboxylic Acid 4-(Trifluoromethyl)-2'-biphenylcarboxylic acid |
| Description | 4'-Trifluoromethyl-2-biphenyl carboxylic acid is an orally active hypolipidemic agent[1]. |
|---|---|
| Related Catalog | |
| In Vivo | 4'-Trifluoromethyl-2-biphenyl carboxylic acid (15-60 mg/kg, p.o., twice a day) shows hypolipidemic activity in diet-induced hypercholesterolemic African green monkeys[1]. Animal Model: Diet-induced hypercholesterolemic African green monkeys[5] Dosage: 15-60 mg/kg Administration: Oral administration (p.o.) Result: Reduced serum LDL-cholesterol concentrations. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 335.8±37.0 °C at 760 mmHg |
| Melting Point | 169-171 °C(lit.) |
| Molecular Formula | C14H9F3O2 |
| Molecular Weight | 266.215 |
| Flash Point | 156.9±26.5 °C |
| Exact Mass | 266.055450 |
| PSA | 37.30000 |
| LogP | 3.97 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.538 |
| Storage condition | Room temperature. |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2916399090 |
| Precursor 10 | |
|---|---|
| DownStream 2 | |
| HS Code | 2916399090 |
|---|---|
| Summary | 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |