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2179-57-9

2179-57-9 structure
2179-57-9 structure

Name diallyl disulfide
Synonyms 2-Propenyl disulfide
3-(prop-2-en-1-yldisulfanyl)prop-1-ene
Diallyl disulfide
EINECS 218-548-6
disulfide, diallyl
Diallyldisulfide
diallyic disulfide
3-(Allyldisulfanyl)prop-1-ene
Allyl disulfide
Disulfide,di-2-propenyl
3-(prop-2-enyldisulfanyl)prop-1-ene
Diallyldisulfide,remainder mainly diallyl sulfide
Allyl disulphide
diallyl disulphide
Disulfide, di-2-propen-1-yl
MFCD00008656
3-(Allyldisulfanyl)-1-propene
4,5-Dithia-1,7-octadiene
diprop-2-en-1-yl disulfide
2-propenyl disulphide
Description Diallyl disulfide inhibits human squalene monooxygenase with an IC50 of 400 μM for squalene epoxidation[1].
Related Catalog
References

[1]. Gupta N, et al. Garlic and garlic-derived compounds inhibit human squalene monooxygenase. J Nutr. 2001;131(6):1662-1667.

Density 1.0±0.1 g/cm3
Boiling Point 185.0±0.0 °C at 760 mmHg
Molecular Formula C6H10S2
Molecular Weight 146.274
Flash Point 42.4±25.8 °C
Exact Mass 146.022385
PSA 50.60000
LogP 3.26
Vapour density >5 (vs air)
Vapour Pressure 1.0±0.3 mmHg at 25°C
Index of Refraction 1.534

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BB1000000
CHEMICAL NAME :
Allyl disulfide
CAS REGISTRY NUMBER :
2179-57-9
BEILSTEIN REFERENCE NO. :
1699241
LAST UPDATED :
199801
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C6-H10-S2
MOLECULAR WEIGHT :
146.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
260 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
878 mg/kg/6D-I
TOXIC EFFECTS :
Endocrine - other changes Endocrine - changes in spleen weight Blood - pigmented or nucleated red blood cells

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
10 mg/L
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 35,379,1997
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315-H319-H335
Precautionary Statements Missing Phrase - N15.00950417-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R10;R22;R36/37/38
Safety Phrases S26-S36/37/39-S37/39-S16
RIDADR UN 2810 6.1/PG 3
WGK Germany 3
RTECS BB1000000
Packaging Group II
Hazard Class 6.1
HS Code 3911900004
HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%