34993-56-1
34993-56-1 structure
- Name: ethynylpyrene
- Chemical Name: 1-ethynylpyrene
- CAS Number: 34993-56-1
- Molecular Formula: C18H10
- Molecular Weight: 226.272
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
- Create Date: 2018-03-28 08:00:00
- Modify Date: 2025-08-25 16:37:25
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1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC50s of 0.18, 0.32, and 0.04 μM, respectively[1].
| Name | 1-ethynylpyrene |
|---|---|
| Synonyms |
8-ethynylpyrene
1-Ethynylpyrene ethynylpyrene Pyrene, 1-ethynyl- 1-Ethynyl Pyrene Pyrene,1-ethynyl MFCD02093933 3-pyrenylacetylene 1-pyrenylacetylene pyrene-1-acetylene ethynyl pyrene |
| Description | 1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC50s of 0.18, 0.32, and 0.04 μM, respectively[1]. |
|---|---|
| Related Catalog | |
| In Vitro | 1-Ethynylpyrene exhibits activity against P450 1A2, and 2B1 with Kis of 0.32 and 0.04 μM, respectively[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 410.6±14.0 °C at 760 mmHg |
| Melting Point | 113-115ºC |
| Molecular Formula | C18H10 |
| Molecular Weight | 226.272 |
| Flash Point | 194.9±14.2 °C |
| Exact Mass | 226.078247 |
| LogP | 5.35 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.807 |
| Safety Phrases | S22-S24/25 |
|---|---|
| HS Code | 2902909090 |
| Precursor 10 | |
|---|---|
| DownStream 2 | |
![Cyclopenta[cd]pyrene structure](https://image.chemsrc.com/caspic/286/27208-37-3.png)
| HS Code | 2902909090 |
|---|---|
| Summary | 2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0% |