- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Icosanedioic acid
- Price: ￥678.0/5g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- Chengdu Pukang Biotechnology Co., Ltd.
- China
- Product Name: Icosanedioic acid
- Price: ￥Inquiry/10g
- Purity: 95.0%
- Stocking Period: Inquiry
- Contact: Lihua Yang
- DC Chemicals Limited
- China
- Product Name: Eicosanedioic acid
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
2424-92-2
2424-92-2 structure
- Name: Icosanedioic acid
- Chemical Name: eicosanedioic acid
- CAS Number: 2424-92-2
- Molecular Formula: C20H38O4
- Molecular Weight: 342.513
- Catalog: Organic raw materials Carboxylic compounds and derivatives Acyclic carboxylic acid
- Create Date: 2018-05-09 08:00:00
- Modify Date: 2024-01-04 20:14:15
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Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis
| Name | eicosanedioic acid |
|---|---|
| Synonyms |
eicosadioic acid
Icosanedioic acid 1,18-Octadecanedicarboxylic acid eicosa-1,20-dioic acid eicosane diacid 1,20-icosanedioic acid Eicossandioic acid eicosandioic acid Eicosanedioic acid MFCD00059627 octadecane-1,18-dicarboxylic acid |
| Description | Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 504.1±23.0 °C at 760 mmHg |
| Melting Point | 127ºC |
| Molecular Formula | C20H38O4 |
| Molecular Weight | 342.513 |
| Flash Point | 272.8±19.1 °C |
| Exact Mass | 342.277008 |
| PSA | 74.60000 |
| LogP | 7.18 |
| Appearance | Powder |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.474 |
| Water Solubility | Slightly soluble in water. |
| Safety Phrases | S22-S24/25 |
|---|---|
| HS Code | 2917190090 |
| Precursor 8 | |
|---|---|
| DownStream 7 | |
| HS Code | 2917190090 |
|---|---|
| Summary | 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |