212118-77-9

212118-77-9 structure

Name: FlAsH-EDT2
Chemical Name: 4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
CAS Number: 212118-77-9
Molecular Formula: C₂₄H₁₈As₂O₅S₄
Molecular Weight: 664.50000
Catalog: Research Areas Others
Create Date: 2016-10-17 00:12:56
Modify Date: 2025-08-25 13:39:54
FlAsH-EDT2 is a protein labeling reagent. FlAsH-EDT2 also is a membrane-permeant fluorogenic biarsenicals. FlAsH-EDT2 binds to CCXXCC motifs and non-specifically to endogenous cysteine-rich proteins. FlAsH-EDT2 can be useful only for labeling those recombinant proteins that express at a very high level[1][2].

Name	4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
Synonyms	flash-edt2

Description	FlAsH-EDT2 is a protein labeling reagent. FlAsH-EDT2 also is a membrane-permeant fluorogenic biarsenicals. FlAsH-EDT2 binds to CCXXCC motifs and non-specifically to endogenous cysteine-rich proteins. FlAsH-EDT2 can be useful only for labeling those recombinant proteins that express at a very high level[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Stroffekova K, et al. The protein-labeling reagent FLASH-EDT2 binds not only to CCXXCC motifs but also non-specifically to endogenous cysteine-rich proteins. Pflugers Arch. 2001 Sep;442(6):859-66. [2]. Adams SR, et al. Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins. Nat Protoc. 2008;3(9):1527-34.