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185517-21-9

185517-21-9 structure
185517-21-9 structure
  • Name: ONO 2506
  • Chemical Name: arundic acid
  • CAS Number: 185517-21-9
  • Molecular Formula: C11H22O2
  • Molecular Weight: 186.29100
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-06-24 16:44:08
  • Modify Date: 2025-08-27 13:12:21
  • Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid (ONO-2506) has been developed as a therapeutic agent for stroke and Alzheimer’s disease[1][2][3].

Name arundic acid
Synonyms 2R-propyloctanoic acid
Artocarpesin
Description Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid (ONO-2506) has been developed as a therapeutic agent for stroke and Alzheimer’s disease[1][2][3].
Related Catalog
References

[1]. Tomoyuki Hasegawa, et al. Process Development of ONO-2506:  A Therapeutic Agent for Stroke and Alzheimer's Disease. Org. Process Res. Dev.200372168-171.

[2]. Kato H, et al. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTPneurotoxicity in mice. Brain Res. 2004 Dec 24;1030(1):66-73.

Density 0.908 g/cm3
Boiling Point 289.3ºC at 760mmHg
Molecular Formula C11H22O2
Molecular Weight 186.29100
Exact Mass 186.16200
PSA 37.30000
LogP 3.45770
Vapour Pressure 0.000557mmHg at 25°C
Index of Refraction 1.444
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