Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Ajoene
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao
Related CAS#:
92285-01-3 92284-99-6
92285-00-2 24138-83-8

92285-01-3

92285-01-3 structure
92285-01-3 structure
  • Name: Ajoene
  • Chemical Name: Allyl[(2E)-3-(allyldisulfanyl)-2-propen-1-yl]sulfoniumolate
  • CAS Number: 92285-01-3
  • Molecular Formula: C9H14OS3
  • Molecular Weight: 234.40200
  • Catalog: Signaling Pathways Anti-infection Fungal
  • Create Date: 2017-10-31 17:52:10
  • Modify Date: 2024-01-08 19:56:31
  • Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities[1][2].
Name Allyl[(2E)-3-(allyldisulfanyl)-2-propen-1-yl]sulfoniumolate
Synonyms (E,Z)-ajoene
2E,4Z-Heptadienal
(E/Z)-4,5,9-trithiadodeca-1,6,11-triene-9-oxide
(E,Z)-2,4-heptadienal
4,5,9-trithiadodeca-1,6,11-triene-9-oxide
(Z,E)-4,5,9-trithiadodeca-1,6,11-triene-9-oxide
(2E,4Z)-2,4-heptadienal
hepta-2t,4c-dienal
2,4-Heptadienal,(E,Z)
Description Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities[1][2].
Related Catalog
In Vitro Ajoene shows cytotoxicity with IC50s in the 7-41 uM range for B16/BL6, HT-29, A549, MDA-MB231, PANC-1, and SKBR-3 cells[1].
In Vivo Ajoene (25 μg/g body weight of Ajoene in 100 mL Intralipid; i.p.; every other day from the day of inoculation up to day 28) inhibits both primary tumor growth[1]. Ajoene (25, 15 or 5 μg/g body weight of Ajoene in 100 μL Intralipid; i.p; every other day over 4 weeks) inhibits strongly metastasis to lung in the B16/BL6 melanoma tumor model in C57BL/6 mice[1].
References

[1]. Taylor P, et al. Ajoene inhibits both primary tumor growth and metastasis of B16/BL6 melanoma cells in C57BL/6 mice. Cancer Lett. 2006;239(2):298-304.

[2]. Ahmed N, et al. Ajoene, a garlic-derived natural compound, enhances chemotherapy-induced apoptosis in human myeloid leukaemia CD34-positive resistant cells. Anticancer Res. 2001;21(5):3519-3523.
Density 1.181g/cm3
Boiling Point 376ºC at 760mmHg
Molecular Formula C9H14OS3
Molecular Weight 234.40200
Flash Point 181.2ºC
Exact Mass 234.02100
PSA 86.88000
LogP 3.86790
Index of Refraction 1.602
HS Code 2930909090
539-86-6 structure

539-86-6

~%

92285-01-3 structure

92285-01-3
Literature: DANMARKS TEKNISKE UNIVERSITET; BJARNSHOLT, Thomas; HOEIBY, Niels; JENSEN, Peter OEstrup; PHIPPS, Richard; SHANMUGHAM, Meenakshi Sundaram; GENNIP, Maria van; CHRISTENSEN, Louise Dahl; JAKOBSEN, Tim Holm; TANNER, David; LARSEN, Thomas Ostenfeld; GIVSKOV, Michael Patent: WO2012/76016 A1, 2012 ; Location in patent: Page/Page column 18-19 ;
2179-57-9 structure

2179-57-9

~%

92285-01-3 structure

92285-01-3
Literature: DANMARKS TEKNISKE UNIVERSITET; BJARNSHOLT, Thomas; HOEIBY, Niels; JENSEN, Peter OEstrup; PHIPPS, Richard; SHANMUGHAM, Meenakshi Sundaram; GENNIP, Maria van; CHRISTENSEN, Louise Dahl; JAKOBSEN, Tim Holm; TANNER, David; LARSEN, Thomas Ostenfeld; GIVSKOV, Michael Patent: WO2012/76016 A1, 2012 ;
HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Chemsrc provides CAS#:92285-01-3 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 92285-01-3 | Chemsrc address: https://www.chemsrc.com/en/baike/91289.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved