15503-87-4

15503-87-4 structure

Name: (15E)-12,18-Dihydroxysenecionan-11,16-dione
Chemical Name: Usaramine
CAS Number: 15503-87-4
Molecular Formula: C₁₈H₂₅NO₆
Molecular Weight: 351.394
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-06-14 19:20:07
Modify Date: 2025-08-25 19:14:45
Usaramine is a pyrrolizidine alkaloid isolated from seeds of Crolatalaria pallida. Usaramine demonstrates a highlighted antibiofilm activity against Staphylococcus epidermidis by reducing more than 50% of biofilm formation without killing the bacteria[1].

Name	Usaramine
Synonyms	trans-Retrorsin C18H25NO6 (15E)-12,18-dihydroxy-senecionane-11,16-dione [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-, (3E,5R,6S,14aR,14bR)- Senecionan-11,16-dione,12,18-dihydroxy-,(15E) trans-Retrorsine (15E)-Retrorsine (15E)-12,18-Dihydroxysenecionan-11,16-dione Mucronatine Usaramin (+)-Ursamine Mucronatine (7CI)

Description	Usaramine is a pyrrolizidine alkaloid isolated from seeds of Crolatalaria pallida. Usaramine demonstrates a highlighted antibiofilm activity against Staphylococcus epidermidis by reducing more than 50% of biofilm formation without killing the bacteria[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. da Silva Negreiros Neto T, et al. Activity of pyrrolizidine alkaloids against biofilm formation and Trichomonas vaginalis. Biomed Pharmacother. 2016 Oct;83:323-329.

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 12,299,1976

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 7,144,1969