97151-02-5
97151-02-5 structure
- Name: α-Hydroxytamoxifen
- Chemical Name: (E)-4-[4-[2-(dimethylamino)ethoxy]phenyl]-3,4-diphenylbut-3-en-2-ol
- CAS Number: 97151-02-5
- Molecular Formula: C26H29NO2
- Molecular Weight: 387.51400
- Catalog: Research Areas Cancer
- Create Date: 2017-07-08 05:54:20
- Modify Date: 2024-01-10 19:15:31
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α-Hydroxytamoxifen is a metabolite of tamoxifen, reacts with DNA in the absence of metabolizing enzymes, and causes formation of DNA adducts[1].
| Name | (E)-4-[4-[2-(dimethylamino)ethoxy]phenyl]-3,4-diphenylbut-3-en-2-ol |
|---|---|
| Synonyms |
trans-(E)-4-[4-(2-dimethylamino-ethoxy)-phenyl]-3,4-diphenyl-but-3-en-2-ol
(E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenyl-1-buten-3-ol Trans-Hydroxy-Tamoxifen (E)-|A-Hydroxy Tamoxifen |
| Description | α-Hydroxytamoxifen is a metabolite of tamoxifen, reacts with DNA in the absence of metabolizing enzymes, and causes formation of DNA adducts[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.094g/cm3 |
|---|---|
| Boiling Point | 533.8ºC at 760 mmHg |
| Melting Point | 115-119ºC |
| Molecular Formula | C26H29NO2 |
| Molecular Weight | 387.51400 |
| Flash Point | 276.6ºC |
| Exact Mass | 387.22000 |
| PSA | 32.70000 |
| LogP | 5.70170 |
| Index of Refraction | 1.595 |
| HS Code | 2922509090 |
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97151-02-5 |
| Literature: Journal of Medicinal Chemistry, , vol. 28, # 10 p. 1491 - 1497 |
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97151-02-5 |
| Literature: Journal of Medicinal Chemistry, , vol. 28, # 10 p. 1491 - 1497 |
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97151-02-5
Detail
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| Literature: Journal of Medicinal Chemistry, , vol. 28, # 10 p. 1491 - 1497 |
| Precursor 3 | |
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| DownStream 0 | |
| HS Code | 2922509090 |
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| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |