Hydroxy derivatives of tamoxifen

AB Foster, M Jarman, OT Leung…

Index: Journal of Medicinal Chemistry, , vol. 28, # 10 p. 1491 - 1497

Full Text: HTML

Citation Number: 109

Abstract

... This work was supported in part by research grants from the National Institutes of General Medical Sciences (Grant GM-25280), the National Insti- tute of Arthritis, ~ i ~ b ~ ~ ~ ~ , and ~ i ~ ~ ~ ~ and Kidney Diseases (Grant AM ... 1492 Journal of Medicinal Chemistry, 1985, Vol. ...

 Related Synthetic Route
1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenyl-1-(4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)butan-1-ol Structure

68047-08-5

1-(4-(2-(dimeth...

~%

4-hydroxytamoxifen Structure

68047-06-3

4-hydroxytamoxifen

(E)-4-Hydroxytamoxifen Structure

174592-47-3

(E)-4-Hydroxyta...

2-(4-Bromophenoxy)tetrahydro-2H-pyran Structure

36603-49-3

2-(4-Bromopheno...

~%

4-hydroxytamoxifen Structure

68047-06-3

4-hydroxytamoxifen

4-Bromophenol Structure

106-41-2

4-Bromophenol

~%

4-hydroxytamoxifen Structure

68047-06-3

4-hydroxytamoxifen

1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenyl-1-(3-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)butan-1-ol Structure

83647-26-1

1-(4-(2-(dimeth...

~%

Droloxifene Structure

82413-20-5

Droloxifene

3-{(Z)-1-[4-(2-DIMETHYLAMINOETHOXY)PHENYL]-2-PHENYLBUT-1-ENYL}PHENOL Structure

83647-29-4

3-{(Z)-1-[4-(2-...

2-(3-Bromophenoxy)tetrahydro-2H-pyran Structure

57999-49-2

2-(3-Bromopheno...

~%

Droloxifene Structure

82413-20-5

Droloxifene

3-Bromophenol Structure

591-20-8

3-Bromophenol

~%

Droloxifene Structure

82413-20-5

Droloxifene

ethyl 2-nitro-3-(4-methoxyphenyl)propionate Structure

61923-53-3

ethyl 2-nitro-3...

~%

cis-a-Hydroxy Tamoxifen Structure

97170-41-7

cis-a-Hydroxy T...

(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene Structure

19118-19-5

(E,Z)-1-Bromo-2...

~%

2-[4-(1,2-diphenylethenyl)phenoxy]-N,N-dimethylethanamine Structure

19957-51-8

2-[4-(1,2-diphe...

α-Hydroxytamoxifen Structure

97151-02-5

α-Hydroxytamoxifen

cis-a-Hydroxy Tamoxifen Structure

97170-41-7

cis-a-Hydroxy T...

(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene Structure

19118-19-5

(E,Z)-1-Bromo-2...

ch3cho Structure

75-07-0

ch3cho

~%

2-[4-(1,2-diphenylethenyl)phenoxy]-N,N-dimethylethanamine Structure

19957-51-8

2-[4-(1,2-diphe...

α-Hydroxytamoxifen Structure

97151-02-5

α-Hydroxytamoxifen

Detail
ethyl 2-nitro-3-(4-methoxyphenyl)propionate Structure

61923-53-3

ethyl 2-nitro-3...

~%

α-Hydroxytamoxifen Structure

97151-02-5

α-Hydroxytamoxifen

(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene Structure

19118-19-5

(E,Z)-1-Bromo-2...

~%

2-[4-(1,2-diphenylethenyl)phenoxy]-N,N-dimethylethanamine Structure

19957-51-8

2-[4-(1,2-diphe...

α-Hydroxytamoxifen Structure

97151-02-5

α-Hydroxytamoxifen

cis-a-Hydroxy Tamoxifen Structure

97170-41-7

cis-a-Hydroxy T...

(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene Structure

19118-19-5

(E,Z)-1-Bromo-2...

ch3cho Structure

75-07-0

ch3cho

~%

2-[4-(1,2-diphenylethenyl)phenoxy]-N,N-dimethylethanamine Structure

19957-51-8

2-[4-(1,2-diphe...

α-Hydroxytamoxifen Structure

97151-02-5

α-Hydroxytamoxifen

Detail
ETHYLENE OXIDE Structure

75-21-8

ETHYLENE OXIDE

(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene Structure

19076-79-0

(E,Z)-1-Bromo-2...

~%

2-[4-(1,2-diphenylethenyl)phenoxy]-N,N-dimethylethanamine Structure

19957-51-8

2-[4-(1,2-diphe...

β-Hydroxy Tamoxifen Structure

97151-03-6

β-Hydroxy Tamoxifen

Detail

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