256498-66-5
256498-66-5 structure
- Name: BAY 41-8543
- Chemical Name: 2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]-5-morpholin-4-ylpyrimidine-4,6-diamine
- CAS Number: 256498-66-5
- Molecular Formula: C21H21FN8O
- Molecular Weight: 420.443
- Create Date: 2017-06-03 16:19:58
- Modify Date: 2024-04-05 16:41:15
-
BAY 41-8543 is an NO-independent sGC (soluble guanylyl cyclase) stimulator, inhibits collagen-mediated aggregation in washed human platelets (IC50=90 nM).
| Name | 2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]-5-morpholin-4-ylpyrimidine-4,6-diamine |
|---|---|
| Synonyms |
4,6-Pyrimidinediamine, 2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-
bay-41-8543 2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine unii-323t2c09sg |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 599.7±50.0 °C at 760 mmHg |
| Molecular Formula | C21H21FN8O |
| Molecular Weight | 420.443 |
| Flash Point | 316.5±30.1 °C |
| Exact Mass | 420.182251 |
| PSA | 121.00000 |
| LogP | -1.16 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.762 |