109-66-0

MOLECULAR FORMULA :

C5-H12

MOLECULAR WEIGHT :

72.17

WISWESSER LINE NOTATION :

5H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

364 gm/m3/4H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(10),23,1988

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

325 gm/m3/2H

TOXIC EFFECTS :

Behavioral - excitement

REFERENCE :

JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 58,74,1936

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

446 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 67,566,1978 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

10 gm/kg/4W-I

REFERENCE :

TIHEEC Toxicology and Industrial Health. (Princeton Scientific Pub. Co., POB 2155, Princeton, NJ 08540) V.1- 1985- Volume(issue)/page/year: 1(3),67,1985 *** REVIEWS *** ACGIH TLV-STEL 2210 mg/m3 (750 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 1770 mg/m3 (600 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 500 ppm (1475 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,200,1971 OSHA PEL (Gen Indu):8H TWA 1000 ppm (2950 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 500 ppm (1500 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 500 ppm (1500 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 1000 ppm (2950 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 600 ppm (1800 mg/m3);STEL 750 ppm (2250 mg/m3) JAN 1993 OEL-BELGIUM:TWA 600 ppm (1770 mg/m3);STEL 750 ppm (2210 mg/m3) JAN 1993 OEL-DENMARK:TWA 500 ppm (1500 mg/m3) JAN 1993 OEL-FINLAND:TWA 500 ppm (1500 mg/m3);STEL 625 ppm (1800 mg/m3) JAN 1993 OEL-FRANCE:TWA 600 ppm (1800 mg/m3) JAN 1993 OEL-GERMANY:TWA 1000 ppm (2950 mg/m3) JAN 1993 OEL-HUNGARY:TWA 500 mg/m3;STEL 1500 mg/m3 JAN 1993 OEL-JAPAN:TWA 300 ppm (880 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 600 ppm (1800 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 1000 ppm (2950 mg/m3) JAN 1993 OEL-POLAND:TWA 100 mg/m3 JAN 1993 OEL-RUSSIA:TWA 300 ppm;STEL 300 mg/m3 JAN 1993 OEL-SWEDEN:TWA 600 ppm (1800 mg/m3);STEL 750 ppm (2000 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 600 ppm (1800 mg/m3) JAN 1993 OEL-TURKEY:TWA 1000 ppm (2950 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 600 ppm (1800 mg/m3);STEL 750 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO PENTANE-air:10H TWA 120 ppm;CL 610 ppm/15M REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 54243 No. of Facilities: 3762 (estimated) No. of Industries: 31 No. of Occupations: 22 No. of Employees: 34548 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 54243 No. of Facilities: 1935 (estimated) No. of Industries: 24 No. of Occupations: 47 No. of Employees: 38465 (estimated) No. of Female Employees: 10889 (estimated)