130263-10-4
130263-10-4 structure
- Name: Demethoxypiplartine
- Chemical Name: 1-[3-(3,4-dimethoxyphenyl)prop-2-enoyl]piperidin-2-one
- CAS Number: 130263-10-4
- Molecular Formula: C16H17NO4
- Molecular Weight: 287.31
- Catalog: Natural product Alkaloid
- Create Date: 2017-08-29 14:08:58
- Modify Date: 2025-08-23 11:32:28
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Demethoxypiplartine is an amide alkaloids which can be isolated from Piper flaviflorum and Piper sarmentosum. Demethoxypiplartine has antifungal activity against Cryptococcus neoformans with the IC50 of 18.1 μg/mL[1].
| Name | 1-[3-(3,4-dimethoxyphenyl)prop-2-enoyl]piperidin-2-one |
|---|---|
| Synonyms |
2(1H)-Pyridinone, 1-[(2E)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propen-1-yl]-5,6-dihydro-
Demethoxypiplartine 1-[(2E)-3-(3,4-Dimethoxyphenyl)-2-propenoyl]-5,6-dihydro-2(1H)-pyridinone |
| Description | Demethoxypiplartine is an amide alkaloids which can be isolated from Piper flaviflorum and Piper sarmentosum. Demethoxypiplartine has antifungal activity against Cryptococcus neoformans with the IC50 of 18.1 μg/mL[1]. |
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| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 449.6±45.0 °C at 760 mmHg |
| Melting Point | 116-117℃ (methanol ) |
| Molecular Formula | C16H17NO4 |
| Molecular Weight | 287.31 |
| Flash Point | 225.7±28.7 °C |
| Exact Mass | 287.115753 |
| PSA | 55.84000 |
| LogP | 2.58 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.593 |
| Hazard Codes | Xi |
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