CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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WE1900000
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CHEMICAL NAME :
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Sodium sulfide
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CAS REGISTRY NUMBER :
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16721-80-5
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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12
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MOLECULAR FORMULA :
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H-Na-S
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MOLECULAR WEIGHT :
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56.06
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WISWESSER LINE NOTATION :
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.NA..S H
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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14600 ug/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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18 mg/kg
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TOXIC EFFECTS :
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Behavioral - coma
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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200 mg/kg
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TOXIC EFFECTS :
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Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - respiratory stimulation Lungs, Thorax, or Respiration - other changes
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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67500 ug/kg/3D-I
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TOXIC EFFECTS :
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Brain and Coverings - other degenerative changes Biochemical - Metabolism (Intermediary) - amino acids (including renal excretion)
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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35 mg/kg/5D-I
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TOXIC EFFECTS :
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Brain and Coverings - other degenerative changes Biochemical - Metabolism (Intermediary) - amino acids (including renal excretion)
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TYPE OF TEST :
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Sex chromosome loss and nondisjunction
MUTATION DATA
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TEST SYSTEM :
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Insect - Drosophila melanogaster
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DOSE/DURATION :
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2000 ppm
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REFERENCE :
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ACBIEF Actualidades Biologicas (Medellin, Colombia). (Universidad de Antioquia, Departamento de Biologia, Apartado Aereo 1226, Medellin, Colombia) V.1- 1972- Volume(issue)/page/year: 14(52),48,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83515 No. of Facilities: 94 (estimated) No. of Industries: 5 No. of Occupations: 10 No. of Employees: 359 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83515 No. of Facilities: 577 (estimated) No. of Industries: 18 No. of Occupations: 34 No. of Employees: 12517 (estimated) No. of Female Employees: 4278 (estimated)
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