Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Sulfolane
Price: ￥158.0/500ml
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Sulfolane
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

126-33-0

126-33-0 structure

Name: Sulfolane
Chemical Name: sulfolane
CAS Number: 126-33-0
Molecular Formula: C₄H₈O₂S
Molecular Weight: 120.170
Catalog: Organic raw materials Organic sulfur compound
Create Date: 2018-07-29 16:57:16
Modify Date: 2025-08-20 12:05:56

Name	sulfolane
Synonyms	Thiocyclopentane-1,1-dioxide bondelanea tetramethylene sulfone SULFOLAN Thiolane-1,1-dioxide Sulfolane Thiophene, tetrahydro-, 1,1-dioxide Tetrahydrothiophene 1,1-dioxide Tetrahydrothiophene, 1,1-dioxide Sulfalone Bondolane A 2,3,4,5-Tetrahydrothiophene-1,1-dioxide 1,1-dioxothiolan 5-17-01-00039 (Beilstein Handbook Reference) MFCD00005484 EINECS 204-783-1 tetrahydro-thiophene-1,1-dioxide SULPHOLANE tetrahydrothiophene dioxide Sulfolone Supholane

Density	1.3±0.1 g/cm3
Boiling Point	285.6±8.0 °C at 760 mmHg
Melting Point	27.4 °C
Molecular Formula	C₄H₈O₂S
Molecular Weight	120.170
Flash Point	165.6±0.0 °C
Exact Mass	120.024498
PSA	42.52000
LogP	-0.77
Vapour density	4.2 (vs air)
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.486
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility	soluble
Freezing Point	26℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XN0700000

CHEMICAL NAME :: Thiophene, tetrahydro-, 1,1-dioxide

CAS REGISTRY NUMBER :: 126-33-0

BEILSTEIN REFERENCE NO. :: 0107765

LAST UPDATED :: 199712

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C4-H8-O2-S

MOLECULAR WEIGHT :: 120.18

WISWESSER LINE NOTATION :: T5SWTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year: 23,302,1966 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1540 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >250 mg/m3/8H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0535072

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year: 23,302,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 4,22,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1620 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0535072

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,560,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1250 mg/kg

TOXIC EFFECTS :: Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 42,97,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1080 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 119,423,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3180 uL/kg

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - other changes Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0535072 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6750 mg/kg/2W-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533719

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 6350 mg/kg/23W-I

TOXIC EFFECTS :: Vascular - pulse pressure increase

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533719

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 495 mg/m3/8H/27D-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Liver - fatty liver degeneration Related to Chronic Data - death

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 40,463,1977

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 200 mg/m3/23H/90D-C

TOXIC EFFECTS :: Blood - changes in leukocyte (WBC) count

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 40,463,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80612 No. of Facilities: 27 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 143 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80612 No. of Facilities: 386 (estimated) No. of Industries: 5 No. of Occupations: 10 No. of Employees: 6635 (estimated) No. of Female Employees: 322 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful
Risk Phrases	R22
Safety Phrases	S23-S25
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	XN0700000
HS Code	29349990

110-01-0

~99%

126-33-0

Literature: Synthetic Communications, , vol. 28, # 16 p. 2983 - 2998

1600-44-8

~66%

126-33-0

Literature: Journal of Organic Chemistry, , vol. 48, # 20 p. 3585 - 3587

110-01-0

~9%

1600-44-8

126-33-0

Literature: Organic Letters, , vol. 1, # 2 p. 189 - 191

110-52-1

~44%

126-33-0

24308-29-0

Literature: Monatshefte fuer Chemie, , vol. 113, p. 37 - 42

4724-56-5

~45%

126-33-0

24308-29-0

Literature: Monatshefte fuer Chemie, , vol. 113, p. 37 - 42

17200-23-6

126-33-0

Literature: US2435404 , ;

110-01-0

1600-44-8

126-33-0

102244-56-4

Literature: Journal of Organic Chemistry, , vol. 67, # 26 p. 9368 - 9378

1192-16-1

126-33-0

Literature: J. Appl. Chem. USSR (Engl. Transl.), , vol. 63, # 6.2. p. 1348 - 1350,1233 - 1235

Precursor 6
110-01-0 1600-44-8 110-52-1 4724-56-5
17200-23-6 1192-16-1
DownStream 10
350-46-9 350-30-1 375-72-4 446-35-5
393-01-1 120770-03-8 21792-52-9 29866-60-2
880-78-4 626-17-5

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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126-33-0	51219-88-6
1003-46-9	24463-84-1
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51275-92-4	1003-78-7
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1018464-53-3	1324002-81-4
1489572-33-9	1247804-10-9
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