222834-30-2

222834-30-2 structure

Name: Ragaglitazar
Chemical Name: [3H]-Ragaglitazar
CAS Number: 222834-30-2
Molecular Formula: C₂₅H₂₅NO₅
Molecular Weight: 419.47000
Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
Create Date: 2016-11-07 13:00:34
Modify Date: 2024-01-10 17:45:11
Ragaglitazar is a PPARα and PPARγ agonist with potent lipid-lowering and insulin-sensitizing efficacy in animal models. Ragaglitazar improves glycemic control and lipid profile in type 2 diabetic.

Name	[3H]-Ragaglitazar
Synonyms	Ragaglitazar

Description	Ragaglitazar is a PPARα and PPARγ agonist with potent lipid-lowering and insulin-sensitizing efficacy in animal models. Ragaglitazar improves glycemic control and lipid profile in type 2 diabetic.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Metabolic Disease
References	[1]. Chakrabarti R, Vikramadithyan RK, Misra P, et al. Ragaglitazar: a novel PPAR alpha PPAR gamma agonist with potent lipid-lowering and insulin-sensitizing efficacy in animal models. Br J Pharmacol. 2003;140(3):527-537. [2]. Saad MF, Greco S, Osei K, et al. Ragaglitazar improves glycemic control and lipid profile in type 2 diabetic subjects: a 12-week, double-blind, placebo-controlled dose-ranging study with an open pioglitazone arm. Diabetes Care. 2004;27(6):1324-1329.