1217623-11-4

1217623-11-4 structure
1217623-11-4 structure
  • Name: N-Desmethyl Zolmitriptan-d3
  • Chemical Name: (5R)-5-[[3-[2-(trideuteriomethylamino)ethyl]-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
  • CAS Number: 1217623-11-4
  • Molecular Formula: C15H16D3N3O2
  • Molecular Weight: 276.35
  • Create Date: 2016-05-25 23:17:39
  • Modify Date: 2024-01-21 15:08:14

Name (5R)-5-[[3-[2-(trideuteriomethylamino)ethyl]-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
Synonyms [2H3]*N-Desmethyl zolmitriptan
Description N-Desmethyl Zolmitriptan-d3 是 N-Desmethyl Zolmitriptan氘代物[1]。
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Molecular Formula C15H16D3N3O2
Molecular Weight 276.35
Exact Mass 276.16700
PSA 69.64000
LogP 1.61160