58096-66-5

58096-66-5 structure

Name: 4′,5′-Didehydro-2′,5′-dideoxyuridine
Chemical Name: 1-[(2R,4S)-4-hydroxy-5-methylideneoxolan-2-yl]pyrimidine-2,4-dione
CAS Number: 58096-66-5
Molecular Formula: C₉H₁₀N₂O₄
Molecular Weight: 210.19
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-01-23 18:57:16
Modify Date: 2024-02-19 00:31:19
4′,5′-Didehydro-2′,5′-dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-[(2R,4S)-4-hydroxy-5-methylideneoxolan-2-yl]pyrimidine-2,4-dione
Synonyms	Uridine,4',5'-didehydro-2',5'-dideoxy

Description	4′,5′-Didehydro-2′,5′-dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Precursor 0
DownStream 1
130108-75-7