128397-09-1

128397-09-1 structure

Name: coleonolic acid
Chemical Name: Hyptadienic acid
CAS Number: 128397-09-1
Molecular Formula: C₃₀H₄₆O₄
Molecular Weight: 470.684
Catalog: Natural product Moss
Create Date: 2017-01-26 12:40:26
Modify Date: 2025-08-25 22:43:10
Hyptadienic acid is a triterpene acid that can be isolated from the leaves of Perilla frutescens. Hyptadienic acid inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice with an ID50 value of 0.13 mg/ear. Hyptadienic acid can be used for the research of inflammation[1].

Name	Hyptadienic acid
Synonyms	coleonolic acid (3aS,5aR,5bS,7aS,10R,11R,11aS,13aS,13bS)-11-Hydroxy-1-(hydroxymethyl)-3,3,5a,5b,10,11,13b-heptamethyl-3,3a,4,5,5a,5b,6,7,8,9,10,11,11a,13,13a,13b-hexadecahydro-7aH-cyclopenta[a]chrysene-7a-carboxylic acid 7aH-Cyclopenta[a]chrysene-7a-carboxylic acid, 3,3a,4,5,5a,5b,6,7,8,9,10,11,11a,13,13a,13b-hexadecahydro-11-hydroxy-1-(hydroxymethyl)-3,3,5a,5b,10,11,13b-heptamethyl-, (3aS,5aR,5bS,7aS,10R,11R,11aS,13aS,13bS)-

Description	Hyptadienic acid is a triterpene acid that can be isolated from the leaves of Perilla frutescens. Hyptadienic acid inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice with an ID50 value of 0.13 mg/ear. Hyptadienic acid can be used for the research of inflammation[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Banno N, et al. Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effects. Biosci Biotechnol Biochem. 2004 Jan;68(1):85-90.

Hazard Codes	Xi