24164-06-5
24164-06-5 structure
- Name: L-Valine,N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-, methyl ester
- Chemical Name: methyl 3-methyl-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]butanoate
- CAS Number: 24164-06-5
- Molecular Formula: C12H23NO4
- Molecular Weight: 245.31500
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2016-08-27 20:55:09
- Modify Date: 2025-08-27 10:07:30
-
NSC 135130 (compound 11a) is a BOC-protected ADC linker that can be linked to tubulin-targeting inhibitors.Can be used to synthesize drug conjugates[1].
| Name | methyl 3-methyl-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]butanoate |
|---|---|
| Synonyms |
methyl n-(tert-butoxycarbonyl)-n-methylvalinate
Boc-L-MeVal-OMe N-Boc-N-Me-L-Val-OMe N-Boc-N-methyl-L-valine methyl ester |
| Description | NSC 135130 (compound 11a) is a BOC-protected ADC linker that can be linked to tubulin-targeting inhibitors.Can be used to synthesize drug conjugates[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.015g/cm3 |
|---|---|
| Boiling Point | 293.5ºC at 760mmHg |
| Molecular Formula | C12H23NO4 |
| Molecular Weight | 245.31500 |
| Flash Point | 131.3ºC |
| Exact Mass | 245.16300 |
| PSA | 55.84000 |
| LogP | 2.05090 |
| Vapour Pressure | 0.00172mmHg at 25°C |
| Index of Refraction | 1.448 |
| HS Code | 2922509090 |
|---|
|
~97%
24164-06-5 |
| Literature: Lan, Hong-Qiao; Ye, Jian-Liang; Wang, Ai-E; Ruan, Yuan-Ping; Huang, Pei-Qiang Chemistry - A European Journal, 2011 , vol. 17, # 3 p. 958 - 968 |
|
~99%
24164-06-5 |
| Literature: Andrus, Merritt B.; Li, Wenke; Keyes, Robert F. Journal of Organic Chemistry, 1997 , vol. 62, # 16 p. 5542 - 5549 |
|
~75%
24164-06-5 |
| Literature: Galeotti, Nathalie; Poncet, Joeel; Chiche, Laurent; Jouin, Patrick Journal of Organic Chemistry, 1993 , vol. 58, # 20 p. 5370 - 5376 |
|
~87%
24164-06-5 |
| Literature: Di Gioia; Barattucci; Bonaccorsi; Leggio; Minuti; Romio; Temperini; Siciliano RSC Advances, 2014 , vol. 4, # 6 p. 2678 - 2686 |
|
~%
24164-06-5 |
| Literature: Andrus, Merritt B.; Li, Wenke; Keyes, Robert F. Journal of Organic Chemistry, 1997 , vol. 62, # 16 p. 5542 - 5549 |
|
~%
24164-06-5 |
| Literature: Di Gioia; Barattucci; Bonaccorsi; Leggio; Minuti; Romio; Temperini; Siciliano RSC Advances, 2014 , vol. 4, # 6 p. 2678 - 2686 |
| Precursor 8 | |
|---|---|
| DownStream 1 | |
| HS Code | 2922509090 |
|---|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |