BioBioPha
China
Product Name: tirotundin
Price: ￥3500.0/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tirotundin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

56377-67-4

56377-67-4 structure

56377-67-4 structure

Name: tirotundin
Chemical Name: Tirotundine
CAS Number: 56377-67-4
Molecular Formula: C₁₉H₂₈O₆
Molecular Weight: 352.42
Catalog: Natural product Sesquiter
Create Date: 2018-03-06 08:00:00
Modify Date: 2024-01-11 15:16:51
Tirotundin (Tagitinin D) is a potent anti-inflammatory agent. Tirotundin inhibits the activation of NF-Kβ[1].

Name	Tirotundine
Synonyms	Propanoic acid, 2-methyl-, (3aS,4R,6S,9R,10S,11aR)-dodecahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester Titrotundine TAGITININ-D (1R,2S,4R,8S,9R,11S)-1-Hydroxy-2,11-dimethyl-7-methylene-6-oxo-5,14-dioxatricyclo[9.2.1.0]tetradec-9-yl 2-methylpropanoate

Description	Tirotundin (Tagitinin D) is a potent anti-inflammatory agent. Tirotundin inhibits the activation of NF-Kβ[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Tirotundin (compound 3) (5, 10, 20, 50 µM; 1 h；随后用 TNF-α 刺激一小时) 在浓度为 50 µM 时完全抑制 NF-Kβ 的激活[1]。
References	[1]. Rüngeler P, et al. Study of three sesquiterpene lactones from Tithonia diversifolia on their anti-inflammatory activity using the transcription factor NF-kappa B and enzymes of the arachidonic acid pathway as targets. Planta Med. 1998 Oct;64(7):588-93.

Density	1.2±0.1 g/cm3
Boiling Point	493.6±45.0 °C at 760 mmHg
Molecular Formula	C₁₉H₂₈O₆
Molecular Weight	352.42
Flash Point	171.1±22.2 °C
Exact Mass	352.188599
PSA	82.06000
LogP	1.86
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.528

Hazard Codes	Xi