1217098-46-8

1217098-46-8 structure
1217098-46-8 structure
  • Name: Glycinexylidide-d6
  • Chemical Name: 2-amino-N-[2,6-bis(trideuteriomethyl)phenyl]acetamide
  • CAS Number: 1217098-46-8
  • Molecular Formula: C10H8D6N2O
  • Molecular Weight: 184.27
  • Create Date: 2017-05-07 16:13:00
  • Modify Date: 2024-01-11 12:22:46

Name 2-amino-N-[2,6-bis(trideuteriomethyl)phenyl]acetamide
Synonyms Glycyl Xylidide-d6
2-Amino-N-(2,6-dimethylphenyl)acetamide-d6
N-Glycyl-2,6-xylidine-d6
Glycinexylidide-d6
2-Amino-2',6'-acetoxylidide-d6
2-Amino-2',6'-dimethylacetanilide-d6
Description Glycinexylidide-d6 是 Glycinexylidide氘代物[1]。
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Molecular Formula C10H8D6N2O
Molecular Weight 184.27
Exact Mass 184.14800
PSA 58.61000
LogP 2.55040