916985-21-2

916985-21-2 structure

Name: CAY10575
Chemical Name: 5-(5,6-dimethoxybenzimidazol-1-yl)-3-[(4-methylsulfonylphenyl)methoxy]thiophene-2-carboxamide
CAS Number: 916985-21-2
Molecular Formula: C₂₂H₂₁N₃O₆S₂
Molecular Weight: 487.549
Catalog: Signaling Pathways NF-κB IKK
Create Date: 2016-05-11 19:07:37
Modify Date: 2024-01-10 15:55:13
IKK2-IN-3 (Compound 8) is an IKK2 inhibitor with an IC50 of 0.075 μM[1].

Name	5-(5,6-dimethoxybenzimidazol-1-yl)-3-[(4-methylsulfonylphenyl)methoxy]thiophene-2-carboxamide
Synonyms	5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[4-(methylsulfonyl)benzyl]oxy}-2-thiophenecarboxamide 2-Thiophenecarboxamide, 5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-[[4-(methylsulfonyl)phenyl]methoxy]- HMS3229L15 5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-{[4-(methylsulfonyl)benzyl]oxy}thiophene-2-carboxamide benzimidazole-thiophene carboxamide,2

Description	IKK2-IN-3 (Compound 8) is an IKK2 inhibitor with an IC50 of 0.075 μM[1].
Related Catalog	Signaling Pathways >> NF-κB >> IKK Research Areas >> Cancer Research Areas >> Inflammation/Immunology
Target	IKK2:0.075 μM (IC50)
References	[1]. Xie HZ, et al. Pharmacophore modeling and hybrid virtual screening for the discovery of novel IκB kinase 2 (IKK2) inhibitors. J Biomol Struct Dyn. 2011 Aug;29(1):165-79.