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1125-01-5

1125-01-5 structure
1125-01-5 structure
  • Name: 3-Azaspiro[5.5]undecane,hydrochloride (1:1)
  • Chemical Name: 3-Azaspiro[5.5]undecane hydrochloride
  • CAS Number: 1125-01-5
  • Molecular Formula: C10H20ClN
  • Molecular Weight: 189.73
  • Catalog: Signaling Pathways Anti-infection Influenza Virus
  • Create Date: 2018-12-15 18:56:23
  • Modify Date: 2024-01-12 12:48:24
  • 3-Azaspiro[5.5]undecane (4,4-Pentamethylenepiperidine) hydrochloride is an inhibitor targeting the WT influenza A virus M2 (A/M2), with an IC50 of 1 μM[1].

Name 3-Azaspiro[5.5]undecane hydrochloride
Synonyms 3-azaspiro[5.5]undecane,hydrochloride
EINECS 214-404-1
Description 3-Azaspiro[5.5]undecane (4,4-Pentamethylenepiperidine) hydrochloride is an inhibitor targeting the WT influenza A virus M2 (A/M2), with an IC50 of 1 μM[1].
Related Catalog
Target

IC50: 1 μM (influenza A virus M2)[1]

References

[1]. Wang J, et al. Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus. ACS Med Chem Lett. 2011 Apr 14;2(4):307-312.  

Boiling Point 273.7ºC at 760 mmHg
Molecular Formula C10H20ClN
Molecular Weight 189.73
Flash Point 119.3ºC
Exact Mass 189.12800
PSA 12.03000
LogP 3.45110
Vapour Pressure 0.00437mmHg at 25°C
Hazard Codes Xi
HS Code 2933990090

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1125-01-5 structure

1125-01-5

Literature: Wang, Jun; Cady, Sarah D.; Balannik, Victoria; Pinto, Lawrence H.; DeGrado, William F.; Hong, Mei Journal of the American Chemical Society, 2009 , vol. 131, p. 8066 - 8076

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1125-01-5 structure

1125-01-5

Literature: DeGrado, William F.; Wang, Jun Patent: US2010/69420 A1, 2010 ; Location in patent: Page/Page column 7 ;
Precursor  2

DownStream  0

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%