Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 6H-thieno[2,3-b]pyrrole-5-carboxylicacid
Price: Check
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 6H-THIENO[2,3-B]PYRROLE-5-CARBOXYLIC ACID
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

51856-25-8

51856-25-8 structure

51856-25-8 structure

Name: DAO-IN-1
Chemical Name: 6h-thieno[2,3-b]pyrrole-5-carboxylic acid
CAS Number: 51856-25-8
Molecular Formula: C₇H₅NO₂S
Molecular Weight: 167.19
Catalog: Research Areas Others
Create Date: 2018-12-29 19:44:16
Modify Date: 2025-08-25 15:53:23
DAO-IN-1 is a potent inhibitor of D-amino acid oxidase (DAO) with an IC50 value of 269 nM. DAO is an enzyme responsible for D-serine metabolism, D-serine is a co-agonist of NMDA receptors[1].

Name	6h-thieno[2,3-b]pyrrole-5-carboxylic acid

Description	DAO-IN-1 is a potent inhibitor of D-amino acid oxidase (DAO) with an IC50 value of 269 nM. DAO is an enzyme responsible for D-serine metabolism, D-serine is a co-agonist of NMDA receptors[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	D-amino acid oxidase (DAO)[1]
References	[1]. Sparey T, et al. The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3386-91.

Density	1.609 g/cm3
Boiling Point	437.4ºC at 760 mmHg
Molecular Formula	C₇H₅NO₂S
Molecular Weight	167.19
Flash Point	218.3ºC
Exact Mass	167.00400
PSA	81.33000
LogP	1.92760

HS Code	2934999090

35357-56-3 structure

35357-56-3

~100%

51856-25-8 structure

51856-25-8

Literature: Keio University Patent: EP2022794 A1, 2009 ; Location in patent: Page/Page column 18; 19 ;

498-62-4 structure

498-62-4

~%

51856-25-8 structure

51856-25-8

Literature: Venable, Jennifer D.; Cai, Hui; Chai, Wenying; Dvorak, Curt A.; Grice, Cheryl A.; Jablonowski, Jill A.; Shah, Chandra R.; Kwok, Annette K.; Ly, Kiev S.; Pio, Barbara; Wei, Jianmei; Desai, Pragnya J.; Jiang, Wen; Nguyen, Steven; Ling, Ping; Wilson, Sandy J.; Dunford, Paul J.; Thurmond, Robin L.; Lovenberg, Timothy W.; Karlsson, Lars; Carruthers, Nicholas I.; Edwards, James P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 26 p. 8289 - 8298

335030-68-7 structure

335030-68-7

~%

51856-25-8 structure

51856-25-8

Literature: Venable, Jennifer D.; Cai, Hui; Chai, Wenying; Dvorak, Curt A.; Grice, Cheryl A.; Jablonowski, Jill A.; Shah, Chandra R.; Kwok, Annette K.; Ly, Kiev S.; Pio, Barbara; Wei, Jianmei; Desai, Pragnya J.; Jiang, Wen; Nguyen, Steven; Ling, Ping; Wilson, Sandy J.; Dunford, Paul J.; Thurmond, Robin L.; Lovenberg, Timothy W.; Karlsson, Lars; Carruthers, Nicholas I.; Edwards, James P. Journal of Medicinal Chemistry, 2005 , vol. 48, # 26 p. 8289 - 8298

118465-49-9 structure

118465-49-9

~%

51856-25-8 structure

51856-25-8

Literature: Whittamore, Paul R.O.; Addie, Matthew S.; Bennett, Stuart N.L.; Birch, Alan M.; Butters, Michael; Godfrey, Linda; Kenny, Peter W.; Morley, Andrew D.; Murray, Paul M.; Oikonomakos, Nikos G.; Otterbein, Ludovic R.; Pannifer, Andrew D.; Parker, Jeremy S.; Readman, Kristy; Siedlecki, Pawel S.; Schofield, Paul; Stocker, Andy; Taylor, Melvyn J.; Townsend, Linda A.; Whalley, David P.; Whitehouse, Jennifer Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 21 p. 5567 - 5571

41405-96-3 structure

41405-96-3

~%

51856-25-8 structure

51856-25-8

Literature: Whittamore, Paul R.O.; Addie, Matthew S.; Bennett, Stuart N.L.; Birch, Alan M.; Butters, Michael; Godfrey, Linda; Kenny, Peter W.; Morley, Andrew D.; Murray, Paul M.; Oikonomakos, Nikos G.; Otterbein, Ludovic R.; Pannifer, Andrew D.; Parker, Jeremy S.; Readman, Kristy; Siedlecki, Pawel S.; Schofield, Paul; Stocker, Andy; Taylor, Melvyn J.; Townsend, Linda A.; Whalley, David P.; Whitehouse, Jennifer Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 21 p. 5567 - 5571

Precursor 5
35357-56-3 498-62-4 335030-68-7 118465-49-9
41405-96-3
DownStream 1
250-79-3

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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