ShangHai DC Chemicals Co.,Ltd
China
Product Name: Bentazepam
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Bentazepam
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

29462-18-8

29462-18-8 structure

Name: Bentazepam
Chemical Name: 5-phenyl-3,4,6,7,8,9-hexahydro-[1]benzothiolo[2,3-e][1,4]diazepin-2-one
CAS Number: 29462-18-8
Molecular Formula: C₁₇H₁₆N₂OS
Molecular Weight: 296.38700
Catalog: Research Areas Neurological Disease
Create Date: 2018-08-26 07:59:15
Modify Date: 2025-09-18 10:22:20
Bentazepam (Thiadipone) is a compound with short-action anxiolytic effect. Bentazepam shows anticonvulsant and sedative properties. Bentazepam can be used for the research of depressive disorder and anxiety[1].

Name	5-phenyl-3,4,6,7,8,9-hexahydro-[1]benzothiolo[2,3-e][1,4]diazepin-2-one
Synonyms	Bentazepam CI-718 Tiadipone Thiadipone 1,3,6,7,8,9-Hexahydro-5-phenyl-2H-(1)benzothieno(2,3-e)-1,4-diazepin-2-one QM-6008 5-phenyl-1,3,6,7,8,9-hexahydro-benzo[4,5]thieno[2,3-e][1,4]diazepin-2-one Bentazepamum [INN-Latin] 2H-(1)BENZOTHIENO(2,3-e)-1,4-DIAZEPIN-2-ONE,1,3,6,7,8,9-HEXAHYDRO-5-PHENYL

Description	Bentazepam (Thiadipone) is a compound with short-action anxiolytic effect. Bentazepam shows anticonvulsant and sedative properties. Bentazepam can be used for the research of depressive disorder and anxiety[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vivo	Bentazepam increases the anticonvulsive activity of clonazepam[1].

Density	1.38g/cm3
Boiling Point	532.6ºC at 760 mmHg
Molecular Formula	C₁₇H₁₆N₂OS
Molecular Weight	296.38700
Flash Point	275.9ºC
Exact Mass	296.09800
PSA	69.70000
LogP	2.99000
Vapour Pressure	2E-11mmHg at 25°C
Index of Refraction	1.733

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DL8230000

CHEMICAL NAME :: 2H-(1)Benzothieno(2,3-e)-1,4-diazepin-2-one, 1,3,6,7,8,9-hexahydro-5-phenyl-

CAS REGISTRY NUMBER :: 29462-18-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C17-H16-N2-O-S

MOLECULAR WEIGHT :: 296.41

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 129 mg/kg/17W-I

TOXIC EFFECTS :: Behavioral - anorexia (human) Behavioral - muscle weakness Liver - liver function tests impaired

REFERENCE :: LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823- Volume(issue)/page/year: 343,860,1994

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,926,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 980 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,926,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 630 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,926,1975

29462-27-9

29462-18-8

Literature: Tinney; Sanchez; Nogas Journal of Medicinal Chemistry, 1974 , vol. 17, # 6 p. 624 - 630

41042-86-8

29462-18-8

Literature: Nakanishi,M. et al. Journal of Medicinal Chemistry, 1973 , vol. 16, p. 214 - 219

43215-25-4

623-33-6

29462-18-8

Literature: Heckendorn; Gagneux Tetrahedron Letters, 1973 , vol. 25, p. 2279 - 2282

Precursor 3
41042-86-8 43215-25-4 623-33-6
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