105-76-0

105-76-0 structure

Name: n-Butyl fumarate
Chemical Name: Dibutyl maleate
CAS Number: 105-76-0
Molecular Formula: C₁₂H₂₀O₄
Molecular Weight: 228.285
Catalog: Chemical reagent Organic reagent Ester Butyl ester compound
Create Date: 2018-05-12 08:00:00
Modify Date: 2025-08-20 11:00:24
Dibutyl maleate, the diester of the Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. Dibutyl maleate can enhance contact sensitization to Fluorescein isothiocyanate in mice[1].

Name	Dibutyl maleate
Synonyms	n-Butyl fumarate maleic acid di-n-butyl ester Di-n-butyl maleate dibutyl 2-methylenesuccinate Butanedioic acid,methylene-,dibutyl ester 2-methylenesuccinic acid dibutyl ester Dibutyl (2E)-2-butenedioate EINECS 203-328-4 Itaconic Acid Dibutyl Ester MFCD00009447 2-Butenedioic acid, dibutyl ester, (2Z)- Dibutyl itaconate Dibutyl (2Z)-2-butenedioate Di(n-butyl) itaconate Methylen-bernsteinsaeure-dibutylester Dibutyl (2Z)-but-2-enedioate Maleic acid dibutyl ester butyl maleate Dibutyl (2E)-but-2-enedioate 2-Butenedioic acid, dibutyl ester, (2E)- n-butyl maleate

Description	Dibutyl maleate, the diester of the Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. Dibutyl maleate can enhance contact sensitization to Fluorescein isothiocyanate in mice[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Matsuoka T, et, al. Dibutyl Maleate and Dibutyl Fumarate Enhance Contact Sensitization to Fluorescein Isothiocyanate in Mice. Biol Pharm Bull. 2016;39(2):272-7.

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/27/1963 ** ACUTE TOXICITY DATA **

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 2,19,1975

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 2,19,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1029 No. of Facilities: 178 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 4094 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1029 No. of Facilities: 37 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 402 (estimated)

Symbol	GHS07, GHS08
Signal Word	Warning
Hazard Statements	H317-H373
Precautionary Statements	P280
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R43;R51/53
Safety Phrases	S26-S36-S61-S37-S29-S24
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	ON0875000
Packaging Group	I; II; III
HS Code	2917190090

HS Code	2917190090
Summary	2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%