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122-03-2

122-03-2 structure
122-03-2 structure
  • Name: 4-Isopropylbenzaldehyde
  • Chemical Name: cuminaldehyde
  • CAS Number: 122-03-2
  • Molecular Formula: C10H12O
  • Molecular Weight: 148.202
  • Catalog: Flavors and spices Synthetic spice Aldehyde Aromatic aldehyde
  • Create Date: 2018-09-25 18:13:11
  • Modify Date: 2024-01-02 13:56:50
  • Cuminaldehyde is the major component of Cuminum cyminum, a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity. Cuminaldehyde shows anticancer activity[1].

Name cuminaldehyde
Synonyms Cuminal
Cuminaldehyde
VHR DY1&1
EINECS 204-516-9
4-propan-2-ylbenzaldehyde
4-Isopropylbenzaldehyde
4-(Propan-2-yl)benzaldehyde
MFCD00006953
4-(1-Methylethyl)benzaldehyde
Cuminic Aldehyde
Benzaldehyde, 4-(1-methylethyl)-
Description Cuminaldehyde is the major component of Cuminum cyminum, a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity. Cuminaldehyde shows anticancer activity[1].
Related Catalog
References

[1]. Morshedi D, et al. Cuminaldehyde as the Major Component of Cuminum cyminum, a Natural Aldehyde with Inhibitory Effect on Alpha-Synuclein Fibrillation and Cytotoxicity. J Food Sci. 2015 Oct;80(10):H2336-45.

Density 1.0±0.1 g/cm3
Boiling Point 236.1±9.0 °C at 760 mmHg
Melting Point 235-236ºC(lit.)
Molecular Formula C10H12O
Molecular Weight 148.202
Flash Point 93.3±0.0 °C
Exact Mass 148.088821
PSA 17.07000
LogP 2.98
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.537
Water Solubility insoluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CU7000000
CHEMICAL NAME :
Benzaldehyde, p-isopropyl-
CAS REGISTRY NUMBER :
122-03-2
BEILSTEIN REFERENCE NO. :
0636547
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H12-O
MOLECULAR WEIGHT :
148.22
WISWESSER LINE NOTATION :
VHR DY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,395,1974 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1390 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - ulceration or bleeding from stomach Liver - other changes
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 2,327,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2400 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 34,1196,1940
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,395,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5141 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1557 (estimated) No. of Female Employees: 276 (estimated)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS CU7000000
Packaging Group I; II; III
HS Code 2912210000
HS Code 2912299000
Summary 2912299000. other cyclic aldehydes without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%