54063-54-6

54063-54-6 structure

Name: Reproterol
Chemical Name: 7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-1,3-dimethylpurine-2,6-dione
CAS Number: 54063-54-6
Molecular Formula: C₁₈H₂₃N₅O₅
Molecular Weight: 389.41
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2018-09-11 15:57:27
Modify Date: 2024-01-11 16:17:07
Reproterol is a dual acting β2-adrenoceptor agonist and PDE inhibitor. The theophylline constituent of Reproterol inhibits phosphodiesterase activity induced by adenylyl cyclase. Reproterol has the potential for asthma research[1][2].

Name	7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-1,3-dimethylpurine-2,6-dione
Synonyms	Reproterol [INN:BAN] EINECS 258-956-1 7-{3-[2-(3,5-dihydroxy-phenyl)-2-hydroxy-ethylamino]-propyl}-1,3-dimethyl-3,7-dihydro-purine-2,6-dione 7-{3-[2-(3,5-dihydroxyphenyl)-2-hydroxyethylamino]-propyl}-theophylline Theophylline,7-(3-((2-(3,5-dihydroxyphenyl)-2-hydroxyethyl)amino)propyl) Reproterolum [INN-Latin] 7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione 7-<3-<2-(3,5-dihydroxyphenyl)-2-hydroxyethylamino>propyl>-theophyllin D 1959 Reproterol

Description	Reproterol is a dual acting β2-adrenoceptor agonist and PDE inhibitor. The theophylline constituent of Reproterol inhibits phosphodiesterase activity induced by adenylyl cyclase. Reproterol has the potential for asthma research[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Inflammation/Immunology
Target	β2 adrenoceptor
References	[1]. Uwe R Juergens, et al. Different mechanisms of action of beta2-adrenergic receptor agonists: a comparison of reproterol, fenoterol and salbutamol on monocyte cyclic-AMP and leukotriene B4 production in vitro. Eur J Med Res. 2004 Jul 30;9(7):365-70. [2]. C G Georgakopoulos, et al. Excretion study of the beta2-agonist reproterol in human urine. J Chromatogr B Biomed Sci Appl. 1999 Apr 16;726(1-2):141-8.

CHEMICAL NAME :: Theophylline, 7-(3-((2-(3,5-dihydroxyphenyl)-2-hydroxyethyl)amino)p ropyl)-

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,14,1977