14348-21-1

14348-21-1 structure

Name: Cnidicin
Chemical Name: cnidicin
CAS Number: 14348-21-1
Molecular Formula: C₂₁H₂₂O₅
Molecular Weight: 354.396
Catalog: Research Areas Others
Create Date: 2018-08-08 12:32:57
Modify Date: 2024-01-09 11:00:33
Cnidicin is a coumarin from the root of Angelica koreana, and inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells[1].

Name	cnidicin
Synonyms	7H-Furo[3,2-g][1]benzopyran-7-one, 4,9-bis[(3-methyl-2-buten-1-yl)oxy]- 4,9-Bis[(3-methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one

Description	Cnidicin is a coumarin from the root of Angelica koreana, and inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Cnidicin shows a significant inhibition upon the release of beta-hexosaminidase from the cultured RBL-2H3 cells in a dose dependent manner (IC50= 25 μM) and upon the nitric oxide production from the activated RAW264.7 cells (IC50=7.5 μM)[1].
References	[1]. Ryu SY, et al. Cnidicin, a coumarin, from the root of Angelica koreana, inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells. Planta Med. 2001 Mar;67(2):172-4.