16034-77-8

16034-77-8 structure

Name: iocetamic acid (200 mg)
Chemical Name: 3-(N-acetyl-3-amino-2,4,6-triiodoanilino)-2-methylpropanoic acid
CAS Number: 16034-77-8
Molecular Formula: C₁₂H₁₃I₃N₂O₃
Molecular Weight: 613.95700
Catalog: API Diagnostic medication Image inspection medication
Create Date: 2018-06-24 15:27:09
Modify Date: 2025-08-21 19:46:50
Cholebrine (DRC 1201), a diagnostic aid, is an orally active chotecystographic contrast agent[1].

Name	3-(N-acetyl-3-amino-2,4,6-triiodoanilino)-2-methylpropanoic acid
Synonyms	Cholimil DRC 1201 Acide iocetamique [INN-French] N-(3-amino-2,4,6-triiodophenyl)-3-acetamido-2-methyl-propionic acid Colebrina IOCETAMIC ACID Acidum jocetamicum Iocetamsaeure Acidum iocetamicum [INN-Latin] Cholebrine Acido iocetamico [INN-Spanish]

Description	Cholebrine (DRC 1201), a diagnostic aid, is an orally active chotecystographic contrast agent[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vivo	Cholebrine 在大鼠中 LD50 为 7 g/kg (口服) 和 0.7 g/kg (静脉注射)[2].
References	[1]. Owen JP, et al. Comparative study of iocetamic acid and calcium ipodate in the visualisation of the gallbladder and common bile duct. Clin Radiol. 1978 Sep;29(5):535-40. [2]. Janbroers JM, et al. Toxicologic studies of iocetamic acid in rats and dogs. Toxicol Appl Pharmacol. 1969 Mar;14(2):242-8.

CHEMICAL NAME :: Propionic acid, 3-(acetyl-(3-amino-2,4,6-triiodophenyl)amino)-2-methy l-

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - other changes

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 14,232,1969

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - other changes

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 14,232,1969

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,997,1970 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6131 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 260 (estimated) No. of Female Employees: 140 (estimated)

HS Code	2924299090

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%