7440-32-6

MOLECULAR FORMULA :

Ti

MOLECULAR WEIGHT :

47.90

WISWESSER LINE NOTATION :

.TI

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intramuscular

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

114 mg/kg/77W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - lymphoma, including Hodgkin's disease Tumorigenic - tumors at site of application

REFERENCE :

NCIUS* Progress Report for Contract No. PH-43-64-886, Submitted to the National Cancer Institute by The Institute of Chemical Biology, University of San Francisco. (San Francisco, CA 94117) Volume(issue)/page/year: PH43-64-886

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Intramuscular

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

360 mg/kg/69W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - lymphoma, including Hodgkin's disease Tumorigenic - tumors at site of application

REFERENCE :

NCIUS* Progress Report for Contract No. PH-43-64-886, Submitted to the National Cancer Institute by The Institute of Chemical Biology, University of San Francisco. (San Francisco, CA 94117) Volume(issue)/page/year: PH43-64-886 ** REPRODUCTIVE DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

158 mg/kg

SEX/DURATION :

multigeneration

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :

AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,102,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 73255 No. of Facilities: 1060 (estimated) No. of Industries: 36 No. of Occupations: 42 No. of Employees: 21978 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5095 No. of Facilities: 9 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 250 (estimated) No. of Female Employees: 53 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5916 No. of Facilities: 6 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 1198 (estimated) No. of Female Employees: 400 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 73255 No. of Facilities: 11591 (estimated) No. of Industries: 113 No. of Occupations: 97 No. of Employees: 189763 (estimated) No. of Female Employees: 9744 (estimated)